Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy

Mitsugumin 53 (MG53), a muscle-specific TRIM family protein, is an essential component of the cell membrane repair machinery. Here we examined the translational value of targeting MG53 function in tissue repair and regenerative medicine. Although native MG53 protein is restricted to skeletal and car...

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Autors principals: Weisleder, Noah, Takizawa, Norio, Lin, Peihui, Wang, Xianhua, Cao, Chunmei, Zhang, Yan, Tan, Tao, Ferrante, Christopher, Zhu, Hua, Chen, Pin-Jung, Yan, Rosalie, Sterling, Matthew, Zhao, Xiaoli, Hwang, Moonsun, Cai, Chuanxi, Cheng, Heping, Takeshima, Hiroshi, Xiao, Ruiping, Ma, Jianjie
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777623/
https://ncbi.nlm.nih.gov/pubmed/22723464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003921
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