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Preclinical Corrective Gene Transfer in Xeroderma Pigmentosum Human Skin Stem Cells
Xeroderma pigmentosum (XP) is a devastating disease associated with dramatic skin cancer proneness. XP cells are deficient in nucleotide excision repair (NER) of bulky DNA adducts including ultraviolet (UV)-induced mutagenic lesions. Approaches of corrective gene transfer in NER-deficient keratinocy...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Nature Publishing Group
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321585/ https://ncbi.nlm.nih.gov/pubmed/22068429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.233 |
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