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Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease

Angiotensin-converting enzyme 2 (ACE2) shares some homology with angiotensin-converting enzyme (ACE) but is not inhibited by ACE inhibitors. The main role of ACE2 is the degradation of Ang II resulting in the formation of angiotensin 1–7 (Ang 1–7) which opposes the actions of Ang II. Increased Ang I...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tikellis, Chris, Thomas, M. C.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321295/
https://ncbi.nlm.nih.gov/pubmed/22536270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/256294
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