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Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease

Angiotensin-converting enzyme 2 (ACE2) shares some homology with angiotensin-converting enzyme (ACE) but is not inhibited by ACE inhibitors. The main role of ACE2 is the degradation of Ang II resulting in the formation of angiotensin 1–7 (Ang 1–7) which opposes the actions of Ang II. Increased Ang I...

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Main Authors: Tikellis, Chris, Thomas, M. C.
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321295/
https://ncbi.nlm.nih.gov/pubmed/22536270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/256294
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