Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney

AIMS: Angiotensin-converting enzyme 2 (ACE2) is the cellular entry point for severe acute respiratory syndrome coronavirus (SARS-CoV-2)—the cause of coronavirus disease 2019 (COVID-19). However, the effect of renin-angiotensin system (RAS)-inhibition on ACE2 expression in human tissues of key releva...

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Pubblicato in:Eur Heart J
Autori principali: Jiang, Xiao, Eales, James M, Scannali, David, Nazgiewicz, Alicja, Prestes, Priscilla, Maier, Michelle, Denniff, Matthew, Xu, Xiaoguang, Saluja, Sushant, Cano-Gamez, Eddie, Wystrychowski, Wojciech, Szulinska, Monika, Antczak, Andrzej, Byars, Sean, Skrypnik, Damian, Glyda, Maciej, Król, Robert, Zywiec, Joanna, Zukowska-Szczechowska, Ewa, Burrell, Louise M, Woolf, Adrian S, Greenstein, Adam, Bogdanski, Pawel, Keavney, Bernard, Morris, Andrew P, Heagerty, Anthony, Williams, Bryan, Harrap, Stephen B, Trynka, Gosia, Samani, Nilesh J, Guzik, Tomasz J, Charchar, Fadi J, Tomaszewski, Maciej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665509/
https://ncbi.nlm.nih.gov/pubmed/33206176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehaa794
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