Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney

AIMS: Angiotensin-converting enzyme 2 (ACE2) is the cellular entry point for severe acute respiratory syndrome coronavirus (SARS-CoV-2)—the cause of coronavirus disease 2019 (COVID-19). However, the effect of renin-angiotensin system (RAS)-inhibition on ACE2 expression in human tissues of key releva...

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Veröffentlicht in:Eur Heart J
Hauptverfasser: Jiang, Xiao, Eales, James M, Scannali, David, Nazgiewicz, Alicja, Prestes, Priscilla, Maier, Michelle, Denniff, Matthew, Xu, Xiaoguang, Saluja, Sushant, Cano-Gamez, Eddie, Wystrychowski, Wojciech, Szulinska, Monika, Antczak, Andrzej, Byars, Sean, Skrypnik, Damian, Glyda, Maciej, Król, Robert, Zywiec, Joanna, Zukowska-Szczechowska, Ewa, Burrell, Louise M, Woolf, Adrian S, Greenstein, Adam, Bogdanski, Pawel, Keavney, Bernard, Morris, Andrew P, Heagerty, Anthony, Williams, Bryan, Harrap, Stephen B, Trynka, Gosia, Samani, Nilesh J, Guzik, Tomasz J, Charchar, Fadi J, Tomaszewski, Maciej
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Clinical Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665509/
https://ncbi.nlm.nih.gov/pubmed/33206176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehaa794
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