Signatures of miR-181a on the Renal Transcriptome and Blood Pressure

MicroRNA-181a binds to the 3′ untranslated region of messenger RNA (mRNA) for renin, a rate-limiting enzyme of the renin-angiotensin system. Our objective was to determine whether this molecular interaction translates into a clinically meaningful effect on blood pressure and whether circulating miR-...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Marques, Francine Z, Romaine, Simon PR, Denniff, Matthew, Eales, James, Dormer, John, Garrelds, Ingrid M, Wojnar, Lukasz, Musialik, Katarzyna, Duda-Raszewska, Barbara, Kiszka, Bartlomiej, Duda, Magdalena, Morris, Brian J, Samani, Nilesh J, Danser, AH Jan, Bogdanski, Pawel, Zukowska-Szczechowska, Ewa, Charchar, Fadi J, Tomaszewski, Maciej
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818264/
https://ncbi.nlm.nih.gov/pubmed/26322847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00096
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