Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure

How a long strand of genomic DNA is compacted into a mitotic chromosome remains one of the basic questions in biology. The nucleosome fibre, in which DNA is wrapped around core histones, has long been assumed to be folded into a 30-nm chromatin fibre and further hierarchical regular structures to fo...

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Autores principales: Nishino, Yoshinori, Eltsov, Mikhail, Joti, Yasumasa, Ito, Kazuki, Takata, Hideaki, Takahashi, Yukio, Hihara, Saera, Frangakis, Achilleas S, Imamoto, Naoko, Ishikawa, Tetsuya, Maeshima, Kazuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321210/
https://ncbi.nlm.nih.gov/pubmed/22343941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.35
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