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Chromosomes without a 30-nm chromatin fiber

How is a long strand of genomic DNA packaged into a mitotic chromosome or nucleus? The nucleosome fiber (beads-on-a-string), in which DNA is wrapped around core histones, has long been assumed to be folded into a 30-nm chromatin fiber, and a further helically folded larger fiber. However, when froze...

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Bibliografske podrobnosti
Main Authors: Joti, Yasumasa, Hikima, Takaaki, Nishino, Yoshinori, Kamada, Fukumi, Hihara, Saera, Takata, Hideaki, Ishikawa, Tetsuya, Maeshima, Kazuhiro
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474659/
https://ncbi.nlm.nih.gov/pubmed/22825571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21222
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