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Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ

Although the formation of 30-nm chromatin fibers is thought to be the most basic event of chromatin compaction, it remains controversial because high-resolution imaging of chromatin in living eukaryotic cells had not been possible until now. Cryo-electron microscopy of vitreous sections is a relativ...

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Detalhes bibliográficos
Main Authors: Eltsov, Mikhail, MacLellan, Kirsty M., Maeshima, Kazuhiro, Frangakis, Achilleas S., Dubochet, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604964/
https://ncbi.nlm.nih.gov/pubmed/19064912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810057105
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