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Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes

Reprogramming gene expression is crucial for DNA replication stress response. We used quantitative proteomics to establish how the transcriptional response results in changes in protein levels. We found that expression of G1/S cell-cycle targets are strongly up-regulated upon replication stress, and...

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Detalhes bibliográficos
Main Authors: Bastos de Oliveira, Francisco M, Harris, Michael R, Brazauskas, Pijus, de Bruin, Robertus A M, Smolka, Marcus B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321206/
https://ncbi.nlm.nih.gov/pubmed/22333912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.27
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