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Phosphorylation of the MBF Repressor Yox1p by the DNA Replication Checkpoint Keeps the G1/S Cell-Cycle Transcriptional Program Active

BACKGROUND: In fission yeast Schizosaccharomyces pombe G1/S cell-cycle regulated transcription depends upon MBF. A negative feedback loop involving Nrm1p and Yox1p bound to MBF leads to transcriptional repression as cells exit G1 phase. However, activation of the DNA replication checkpoint response...

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Main Authors: Caetano, Catia, Klier, Steffi, de Bruin, Robertus A. M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040222/
https://ncbi.nlm.nih.gov/pubmed/21359180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017211
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