The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback

The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wave regulated by transcription factor complexes termed MBF/SBF in yeast and E2F-DP in mammals. Here we apply genomic, genetic, and biochemical approaches...

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Autors principals: Aligianni, Sofia, Lackner, Daniel H., Klier, Steffi, Rustici, Gabriella, Wilhelm, Brian T., Marguerat, Samuel, Codlin, Sandra, Brazma, Alvis, de Bruin, Robertus A. M., Bähler, Jürg
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726434/
https://ncbi.nlm.nih.gov/pubmed/19714215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000626
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