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Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence
The t(8;21) and t(16;21) that are associated with acute myeloid leukaemia disrupt two closely related genes termed Myeloid Translocation Genes 8 (MTG8) and 16 (MTG16), respectively. Many of the transcription factors that recruit Mtg16 regulate haematopoietic stem and progenitor cell functions and ar...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321173/ https://ncbi.nlm.nih.gov/pubmed/22266796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.500 |
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