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Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence

The t(8;21) and t(16;21) that are associated with acute myeloid leukaemia disrupt two closely related genes termed Myeloid Translocation Genes 8 (MTG8) and 16 (MTG16), respectively. Many of the transcription factors that recruit Mtg16 regulate haematopoietic stem and progenitor cell functions and ar...

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Detalhes bibliográficos
Main Authors: Fischer, Melissa A, Moreno-Miralles, Isabel, Hunt, Aubrey, Chyla, Brenda J, Hiebert, Scott W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321173/
https://ncbi.nlm.nih.gov/pubmed/22266796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.500
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