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Mtg16/Eto2 Contributes to Murine T-Cell Development

Mtg16/Eto2 is a transcriptional corepressor that is disrupted by t(16;21) in acute myeloid leukemia. Using mice lacking Mtg16, we found that Mtg16 is a critical regulator of T-cell development. Deletion of Mtg16 led to reduced thymocyte development in vivo, and after competitive bone marrow transpla...

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Detalhes bibliográficos
Main Authors: Hunt, Aubrey, Fischer, Melissa, Engel, Michael E., Hiebert, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133377/
https://ncbi.nlm.nih.gov/pubmed/21536648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01458-10
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