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Mtg16/Eto2 Contributes to Murine T-Cell Development
Mtg16/Eto2 is a transcriptional corepressor that is disrupted by t(16;21) in acute myeloid leukemia. Using mice lacking Mtg16, we found that Mtg16 is a critical regulator of T-cell development. Deletion of Mtg16 led to reduced thymocyte development in vivo, and after competitive bone marrow transpla...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133377/ https://ncbi.nlm.nih.gov/pubmed/21536648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01458-10 |
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