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Myeloid Translocation Gene 16 (MTG16) Interacts with Notch Transcription Complex Components To Integrate Notch Signaling in Hematopoietic Cell Fate Specification

The Notch signaling pathway regulates gene expression programs to influence the specification of cell fate in diverse tissues. In response to ligand binding, the intracellular domain of the Notch receptor is cleaved by the γ-secretase complex and then translocates to the nucleus. There, it binds the...

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Autores principales: Engel, Michael E., Nguyen, Hong N., Mariotti, Jolene, Hunt, Aubrey, Hiebert, Scott W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838074/
https://ncbi.nlm.nih.gov/pubmed/20123979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01342-09
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