Effect of Carcinogenic Acrolein on DNA Repair and Mutagenic Susceptibility

Acrolein (Acr), a ubiquitous environmental contaminant, is a human carcinogen. Acr can react with DNA to form mutagenic α- and γ-hydroxy-1, N(2)-cyclic propano-2′-deoxyguanosine adducts (α-OH-Acr-dG and γ-OH-Acr-dG). We demonstrate here that Acr-dG adducts can be efficiently repaired by the nucleoti...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Wang, Hsiang-Tsui, Hu, Yu, Tong, Dan, Huang, Jian, Gu, Liya, Wu, Xue-Ru, Chung, Fung-Lung, Li, Guo-Min, Tang, Moon-shong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
DNA and Chromosomes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320987/
https://ncbi.nlm.nih.gov/pubmed/22275365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.329623
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller