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α-Catenin Inhibits β-Catenin-T-cell Factor/Lymphoid Enhancing Factor Transcriptional Activity and Collagen Type II Expression in Articular Chondrocytes through Formation of Gli3R·α-Catenin·β-Catenin Ternary Complex

Chondrocytes, a unique cell type in cartilage tissue, are responsible for the regulation of anabolic and catabolic homeostasis in cartilage-specific extracellular matrix synthesis. Activation of Wnt/β-catenin signaling induces dedifferentiation of articular chondrocytes, resulting in suppression of...

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Detalhes bibliográficos
Main Authors: Rhee, Jinseol, Ryu, Je-Hwang, Kim, Jin-Hong, Chun, Churl-Hong, Chun, Jang-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320923/
https://ncbi.nlm.nih.gov/pubmed/22298781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281014
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