Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates.

Oligonucleotide (2-aminoethyl)phosphonates in which the backbone consisted of isomerically pure, alternating (2-aminoethyl)-phosphonate and phosphodiester linkages have been prepared and characterized. One of these single isomer oligonucleotides (Rp) formed a more stable duplex with DNA or RNA than...

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Bibliographische Detailangaben
Hauptverfasser: Fathi, R, Huang, Q, Coppola, G, Delaney, W, Teasdale, R, Krieg, A M, Cook, A F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC332091/
https://ncbi.nlm.nih.gov/pubmed/7816633
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