Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates.
Oligonucleotide (2-aminoethyl)phosphonates in which the backbone consisted of isomerically pure, alternating (2-aminoethyl)-phosphonate and phosphodiester linkages have been prepared and characterized. One of these single isomer oligonucleotides (Rp) formed a more stable duplex with DNA or RNA than...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1994
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5416 |
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