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Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates.

Oligonucleotide (2-aminoethyl)phosphonates in which the backbone consisted of isomerically pure, alternating (2-aminoethyl)-phosphonate and phosphodiester linkages have been prepared and characterized. One of these single isomer oligonucleotides (Rp) formed a more stable duplex with DNA or RNA than...

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Publicat a:Nucleic Acids Res
Autors principals: Fathi, R, Huang, Q, Coppola, G, Delaney, W, Teasdale, R, Krieg, A M, Cook, A F
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1994
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5416
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