Toolbox for Non-Intrusive Structural and Functional Analysis of Recombinant VLP Based Vaccines: A Case Study with Hepatitis B Vaccine

BACKGROUND: Fundamental to vaccine development, manufacturing consistency, and product stability is an understanding of the vaccine structure-activity relationship. With the virus-like particle (VLP) approach for recombinant vaccines gaining popularity, there is growing demand for tools that define...

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Autori principali: Mulder, Anke M., Carragher, Bridget, Towne, Victoria, Meng, Yuan, Wang, Yang, Dieter, Lance, Potter, Clinton S., Washabaugh, Michael W., Sitrin, Robert D., Zhao, Qinjian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320896/
https://ncbi.nlm.nih.gov/pubmed/22493667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033235
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