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Chromosomal translocations are guided by the spatial organization of the genome
The extent to which the three dimensional organization of the genome contributes to chromosomal translocations is an important question in cancer genomics. We now have generated a high resolution Hi-C spatial organization map of the G1-arrested mouse pro-B cell genome and mapped translocations from...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320767/ https://ncbi.nlm.nih.gov/pubmed/22341456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.002 |
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