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Daunomycin modifies the sequence-selective recognition of DNA by actinomycin.
The antitumour antibiotic actinomycin D normally binds to DNA by intercalation at sequences containing the CpG step, but in the presence of daunomycin it has been reported to interact with poly(dA-dT). This observation has neither been confirmed nor explained. Here we have used a photoreactive 7-azi...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1994
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC332067/ https://ncbi.nlm.nih.gov/pubmed/7816612 |
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