Sequence-selective binding to DNA of bis(amidinophenoxy)alkanes related to propamidine and pentamidine.

The DNA sequences targeted by a complete homologous series of aromatic diamidines have been determined at single-nucleotide resolution via protection from cutting by the endonucleases DNase I, DNase II and micrococcal nuclease. Propamidine, pentamidine and to a lesser extent hexamidine bind selectiv...

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Autors principals: Bailly, C, Perrine, D, Lancelot, J C, Saturnino, C, Robba, M, Waring, M J
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218299/
https://ncbi.nlm.nih.gov/pubmed/9173886
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