Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa

The type III secretion system (T3SS) is a complex macromolecular machinery employed by a number of Gram-negative pathogens to inject effectors directly into the cytoplasm of eukaryotic cells. ExoU from the opportunistic pathogen Pseudomonas aeruginosa is one of the most aggressive toxins injected by...

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Main Authors: Gendrin, Claire, Contreras-Martel, Carlos, Bouillot, Stéphanie, Elsen, Sylvie, Lemaire, David, Skoufias, Dimitrios A., Huber, Philippe, Attree, Ina, Dessen, Andréa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320612/
https://ncbi.nlm.nih.gov/pubmed/22496657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002637
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