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Induced Conformational Changes in the Activation of the Pseudomonas aeruginosa type III Toxin, ExoU
ExoU is a 74-kDa, water-soluble toxin injected directly into mammalian cells through the type III secretion system of the opportunistic pathogen, Pseudomonas aeruginosa. Previous studies have shown that ExoU is a Ca(2+)-independent phospholipase that requires a eukaryotic protein cofactor. One prote...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043214/ https://ncbi.nlm.nih.gov/pubmed/21354407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.01.056 |
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