Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference

Cocaine blocks uptake by neuronal plasma membrane transporters for dopamine (DAT), serotonin (SERT), and norepinephrine (NET). Cocaine reward/reinforcement has been linked to actions at DAT or to blockade of SERT. However, knockouts of neither DAT, SERT, or NET reduce cocaine reward/reinforcement, l...

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Autores principales: Sora, Ichiro, Hall, F. Scott, Andrews, Anne M., Itokawa, Masanari, Li, Xiao-Fei, Wei, Hong-Bing, Wichems, Christine, Lesch, Klaus-Peter, Murphy, Dennis L., Uhl, George R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC33204/
https://ncbi.nlm.nih.gov/pubmed/11320258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091039298
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