Constructing Atomic-Resolution RNA Structural Ensembles Using MD and Motionally Decoupled NMR RDCs

A broad structural landscape often needs to be characterized in order to fully understand how regulatory RNAs perform their biological functions at the atomic level. We present a protocol for visualizing thermally accessible RNA conformations at atomic-resolution and with timescales extending up to...

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Autores principales: Stelzer, Andrew C., Frank, Aaron T., Bailor, Maximillian H., Andricioaei, Ioan, Al-Hashimi, Hashim M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320149/
https://ncbi.nlm.nih.gov/pubmed/19699798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.08.006
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