Constructing Atomic-Resolution RNA Structural Ensembles Using MD and Motionally Decoupled NMR RDCs

A broad structural landscape often needs to be characterized in order to fully understand how regulatory RNAs perform their biological functions at the atomic level. We present a protocol for visualizing thermally accessible RNA conformations at atomic-resolution and with timescales extending up to...

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Bibliographic Details
Main Authors: Stelzer, Andrew C., Frank, Aaron T., Bailor, Maximillian H., Andricioaei, Ioan, Al-Hashimi, Hashim M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320149/
https://ncbi.nlm.nih.gov/pubmed/19699798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.08.006
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