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Toxoplasma gondii profilin acts primarily to sequester G-actin while formins efficiently nucleate actin filament formation in vitro

Apicomplexan parasites employ gliding motility that depends on the polymerization of parasite actin filaments for host cell entry. Despite this requirement, parasite actin remains almost entirely unpolymerized at steady state; formation of filaments required for motility relies on a small repertoire...

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Bibliografische gegevens
Hoofdauteurs: SKILLMAN, Kristen M., DAHER, Wassim, Christopher, I., SOLDATI-FAVRE, Dominique, SIBLEY, L. David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319672/
https://ncbi.nlm.nih.gov/pubmed/22397711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201704y
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