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Toxoplasma gondii profilin acts primarily to sequester G-actin while formins efficiently nucleate actin filament formation in vitro

Apicomplexan parasites employ gliding motility that depends on the polymerization of parasite actin filaments for host cell entry. Despite this requirement, parasite actin remains almost entirely unpolymerized at steady state; formation of filaments required for motility relies on a small repertoire...

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Detalhes bibliográficos
Main Authors: SKILLMAN, Kristen M., DAHER, Wassim, Christopher, I., SOLDATI-FAVRE, Dominique, SIBLEY, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319672/
https://ncbi.nlm.nih.gov/pubmed/22397711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201704y
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