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STRIATAL ATROPHY AND DENDRITIC ALTERATIONS IN A KNOCK-IN MOUSE MODEL OF HUNTINGTON’S DISEASE

Huntington’s disease (HD) is a progressive neurodegenerative disease characterized by progressive atrophy of the striatum, cerebral cortex, and white matter tracks. Major pathological hallmarks of HD include neuronal loss, primarily in the striatum, and dendritic anomalies in surviving striatal neur...

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Autors principals: Lerner, Renata P., Trejo Martinez, Luz del Carmen G., Zhu, Chunni, Chesselet, Marie-Françoise, Hickey, Miriam A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319635/
https://ncbi.nlm.nih.gov/pubmed/22326483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2012.01.012
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