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Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models

In addition to the hallmark neurological manifestations of Huntington's disease (HD), weight loss with metabolic dysfunction is often observed in the later stages of disease progression and is associated with poor prognosis. The mechanism for weight loss in HD is unknown. Using two mouse models...

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Main Authors: Phan, Jack, Hickey, Miriam A., Zhang, Peixiang, Chesselet, Marie-Francoise, Reue, Karen
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649017/
https://ncbi.nlm.nih.gov/pubmed/19124532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn428
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