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Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models

In addition to the hallmark neurological manifestations of Huntington's disease (HD), weight loss with metabolic dysfunction is often observed in the later stages of disease progression and is associated with poor prognosis. The mechanism for weight loss in HD is unknown. Using two mouse models...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Phan, Jack, Hickey, Miriam A., Zhang, Peixiang, Chesselet, Marie-Francoise, Reue, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649017/
https://ncbi.nlm.nih.gov/pubmed/19124532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn428
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