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NMR studies on the binding of antitumor drug nogalamycin to DNA hexamer d(CGTACG).

The interactions between a novel antitumor drug nogalamycin with the self-complementary DNA hexamer d(CGTACG) have been studied by 500 MHz two dimensional proton nuclear magnetic resonance spectroscopy. When two nogalamycins are mixed with the DNA hexamer duplex in a 2:1 ratio, a symmetrical complex...

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Udgivet i:Nucleic Acids Res
Principais autores: Robinson, H, Liaw, Y C, van der Marel, G A, van Boom, J H, Wang, A H
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1990
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2395646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.16.4851
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