NMR studies on the binding of antitumor drug nogalamycin to DNA hexamer d(CGTACG).

The interactions between a novel antitumor drug nogalamycin with the self-complementary DNA hexamer d(CGTACG) have been studied by 500 MHz two dimensional proton nuclear magnetic resonance spectroscopy. When two nogalamycins are mixed with the DNA hexamer duplex in a 2:1 ratio, a symmetrical complex...

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Hauptverfasser: Robinson, H, Liaw, Y C, van der Marel, G A, van Boom, J H, Wang, A H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331962/
https://ncbi.nlm.nih.gov/pubmed/2395646
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