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Transcriptional Drivers of the T-cell Lineage Program

The T-cell development program is specifically triggered by Notch-Delta signaling, but most transcription factors needed to establish T-cell lineage identity also have crossover roles in other hematopoietic lineages. This factor sharing complicates full definition of the core gene regulatory circuit...

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Detalhes bibliográficos
Autor principal: Rothenberg, Ellen V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319509/
https://ncbi.nlm.nih.gov/pubmed/22264928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.12.012
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