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Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
Genetic alterations and epigenetic dysregulation in cancer cells create a vast array of neoepitopes potentially recognizable by the immune system. Immune checkpoint blockade has the capacity to enhance and sustain endogenous immunity against non-mutated tumor-associated antigens as well as uniquely...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319479/ https://ncbi.nlm.nih.gov/pubmed/22236695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.12.009 |
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