Evaluation of Lassa antiviral compound ST-193 in a guinea pig model

Lassa virus (LASV), a member of the Arenaviridae family, causes a viral hemorrhagic fever endemic to West Africa, where as many as 300,000 infections occur per year. Presently, there are no FDA-approved LASV-specific vaccines or antiviral agents, although the antiviral drug ribavirin has shown some...

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Hauptverfasser: Cashman, Kathleen A., Smith, Mark A., Twenhafel, Nancy A., Larson, Ryan A., Jones, Kevin F., Allen, Robert D., Dai, Dongcheng, Chinsangaram, Jarasvech, Bolken, Tove’ C., Hruby, Dennis E., Amberg, Sean M., Hensley, Lisa E., Guttieri, Mary C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. Published by Elsevier B.V. 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319460/
https://ncbi.nlm.nih.gov/pubmed/21371508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.02.012
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