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EX VIVO SPINAL CORD SLICE MODEL OF NEUROMYELITIS OPTICA REVEALS NOVEL IMMUNOPATHOGENIC MECHANISMS
OBJECTIVE: Neuromyelitis optica (NMO) is a neuroinflammatory disease of spinal cord and optic nerve associated with serum autoantibodies (NMO-IgG) against astrocyte water channel aquaporin-4 (AQP4). Recent studies suggest that AQP4 autoantibodies are pathogenic. The objectives of this study were to...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319401/ https://ncbi.nlm.nih.gov/pubmed/22069219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22551 |
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