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Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica

Eosinophils are abundant in inflammatory demyelinating lesions in neuromyelitis optica (NMO). We used cell culture, ex vivo spinal cord slices, and in vivo mouse models of NMO to investigate the role of eosinophils in NMO pathogenesis and the therapeutic potential of eosinophil inhibitors. Eosinophi...

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Detalhes bibliográficos
Main Authors: Zhang, Hua, Verkman, A.S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635742/
https://ncbi.nlm.nih.gov/pubmed/23563310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67554
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