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Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica

Eosinophils are abundant in inflammatory demyelinating lesions in neuromyelitis optica (NMO). We used cell culture, ex vivo spinal cord slices, and in vivo mouse models of NMO to investigate the role of eosinophils in NMO pathogenesis and the therapeutic potential of eosinophil inhibitors. Eosinophi...

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Hlavní autoři: Zhang, Hua, Verkman, A.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635742/
https://ncbi.nlm.nih.gov/pubmed/23563310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67554
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