Pro-Inflammatory Role of Leukocyte Derived Egr-1 in the Development of Murine Postoperative Ileus

BACKGROUND AND AIMS: Early growth response gene-1 (Egr-1) is an important inflammatory transcription factor. We hypothesize that leukocyte-derived Egr-1 plays a key inflammatory role in causing postoperative ileus. METHODS: Wild-type, Egr-1 knockout and chimera WT mice (constructed by irradiation fo...

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Hauptverfasser: Schmidt, Joachim, Stoffels, Burkhard, Moore, Beverley A., Chanthaphavong, R. Savanh, Mazie, Abigail R., Buchholz, Bettina, Bauer, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319384/
https://ncbi.nlm.nih.gov/pubmed/18652830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.05.079
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