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Probing the folding transition state of ubiquitin mutants by temperature-jump induced downhill unfolding
Crucial to revealing mechanistic details of protein folding is a characterization of the transition state ensemble and its structural dynamics. To probe the transition state of ubiquitin thermal unfolding, we examine unfolding dynamics and kinetics of wildtype and mutant ubiquitin using time-resolve...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319365/ https://ncbi.nlm.nih.gov/pubmed/19053229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801603e |
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