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Probing the folding transition state of ubiquitin mutants by temperature-jump induced downhill unfolding

Crucial to revealing mechanistic details of protein folding is a characterization of the transition state ensemble and its structural dynamics. To probe the transition state of ubiquitin thermal unfolding, we examine unfolding dynamics and kinetics of wildtype and mutant ubiquitin using time-resolve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chung, Hoi Sung, Shandiz, Ali, Sosnick, Tobin R., Tokmakoff, Andrei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319365/
https://ncbi.nlm.nih.gov/pubmed/19053229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801603e
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