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Probing the folding transition state of ubiquitin mutants by temperature-jump induced downhill unfolding

Crucial to revealing mechanistic details of protein folding is a characterization of the transition state ensemble and its structural dynamics. To probe the transition state of ubiquitin thermal unfolding, we examine unfolding dynamics and kinetics of wildtype and mutant ubiquitin using time-resolve...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chung, Hoi Sung, Shandiz, Ali, Sosnick, Tobin R., Tokmakoff, Andrei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319365/
https://ncbi.nlm.nih.gov/pubmed/19053229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801603e
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