APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

The pathogenic model of Alzheimer's disease (AD) posits that aggregates of amyloid β, a product of amyloid precursor protein (APP) processing, cause dementia. However, alterations of normal APP functions could contribute to AD pathogenesis, and it is therefore important to understand the role o...

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Autori principali: Matrone, Carmela, Barbagallo, Alessia P.M., La Rosa, Luca R., Florenzano, Fulvio, Ciotti, Maria T., Mercanti, Delio, Chao, Moses V., Calissano, Pietro, D'Adamio, Luciano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
Soggetti:
Brief Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319322/
https://ncbi.nlm.nih.gov/pubmed/21849536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1960-11.2011
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