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The Naphthol Selective Estrogen Receptor Modulator (SERM), LY2066948, is Oxidized to an o-Quinone Analogous to the Naphthol Equine Estrogen, Equilenin
o-Quinone forming estrogens and selective estrogen receptor modulators (SERMs) have been associated with carcinogenesis. LY2066948, a novel SERM in development by Eli Lilly for the treatment of uterine fibroids and myomas, has structural similarity to the equine estrogen equilenin present in hormone...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319273/ https://ncbi.nlm.nih.gov/pubmed/22290292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.01.004 |
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