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Ionizing Radiation-Induced Mutant Frequencies Increase Transiently in Male Germ Cells of Older Mice
Spontaneous mutant frequency in the male germline increases with age, thereby increasing the risk of siring offspring with genetic disorders. In the present study we investigated the effect of age on ionizing radiation-induced male germline mutagenesis. lacI transgenic mice were treated with ionizin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319269/ https://ncbi.nlm.nih.gov/pubmed/22314132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2012.01.003 |
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