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Enhanced Genetic Integrity in Mouse Germ Cells

Genetically based diseases constitute a major human health burden, and de novo germline mutations represent a source of heritable genetic alterations that can cause such disorders in offspring. The availability of transgenic rodent systems with recoverable, mutation reporter genes has been used to a...

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Bibliographic Details
Published in:Biol Reprod
Main Authors: Murphey, Patricia, McLean, Derek J., McMahan, C. Alex, Walter, Christi A., McCarrey, John R.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434944/
https://ncbi.nlm.nih.gov/pubmed/23153565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.103481
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