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Sequence-Specific B-DNA Flexibility Modulates Z-DNA Formation

Conversion of right-handed B-DNA into left-handed Z-DNA is one of the largest structural transitions in biology that plays fundamental roles in gene expression and regulation. Z-DNA segments must form within genomes surrounded by a sea of B-DNA and require creation of energetically costly B/Z juncti...

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Autores principales: Bothe, Jameson R., Lowenhaupt, Ky, Al-Hashimi, Hashim M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319140/
https://ncbi.nlm.nih.gov/pubmed/21275369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1073068
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