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Incorporation of CC Steps into Z-DNA: Interplay Between B/Z Junction and Z-DNA Helical Formation

The left-handed DNA structure, Z-DNA, is believed to play important roles in gene expression and regulation. Z-DNA forms sequence-specifically with a preference for sequences rich in pyrimidine/purine dinucleotide steps. In vivo, Z-DNA is generated in the presence of negative supercoiling or upon bi...

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Detalhes bibliográficos
Main Authors: Bothe, Jameson R., Lowenhaupt, Ky, Al-Hashimi, Hashim M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676945/
https://ncbi.nlm.nih.gov/pubmed/22873788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300785b
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